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Why you can't buy antibiotics or strong painkillers at Japanese drugstores, what is prescription-only by law, and where travelers in Kyoto can actually get them.

“My throat hurts badly.” “I have a terrible toothache and can’t sleep.” “I think I have a urinary tract infection (UTI).”
In your home country, a quick visit to a nearby pharmacy and a chat with a pharmacist might be enough to get you antibiotics or strong painkillers. However, in Japan, this approach does not work.
Japan has very strict laws regarding medication sales. If you don’t know the boundary between what you can and cannot buy, you might end up wandering from drugstore to drugstore while enduring your pain.
The following medications require a doctor’s prescription by Japanese law. You cannot buy them directly off the shelf at a drugstore.
This is the biggest hurdle for travelers. Medications like amoxicillin or azithromycin require a prescription 100% of the time in Japan. Even if you suspect a sinus infection from a cold, bacterial food poisoning, or a UTI, over-the-counter (OTC) drugs cannot treat the root cause. Japanese drugstore medicines are designed to soothe symptoms, not to kill bacteria.
Japanese OTC painkillers (such as ibuprofen or loxoprofen) generally have lower dosage limits compared to Western standards. Additionally, stronger painkillers or specific opioid-based medications are not sold over the counter. If you are experiencing severe pain that standard OTC meds cannot relieve, do not try to compensate by taking more pills — you need a proper medical prescription.
Steroid tablets for severe allergies and inhalers for asthma attacks are also prescription-only items. If you forgot your medication at home, a pharmacy cannot provide a substitute.
“I was turned away at the pharmacy, but I don’t want to go to a massive hospital…”
If you are hesitating, please come to Dr. Coming International Clinic Kyoto Station, on the 6th floor of Hotel Granvia Kyoto, directly accessible from JR Kyoto Station.
Curious which of your usual medications are unavailable here? See our companion guides: 10 Common Western Drugs Unavailable in Japan (Part 1) and Restricted Medications & Legal Risks (Part 2).
Don’t waste your precious travel time lining up at a drugstore only to be told “no.” Especially if you need antibiotics or relief from severe pain, do not try to solve it yourself — rely on a professional.
Dr. Coming International Clinic Kyoto Station is ready to respond to your urgent need for medication with smooth multilingual support and convenient access.
Medication and regulatory information in this article is current as of August 2026.